Lindane lotion and lindane shampoo questions and answers. [42], Lindane is a persistent organic pollutant: it is relatively long-lived in the environment, it is transported long distances by natural processes like global distillation, and it can bioaccumulate in food chains, though it is rapidly eliminated when exposure is discontinued. "[7] The U.S. Department of Health and Human Services determined that all isomers of hexachlorocyclohexane, including lindane, "may reasonably be anticipated to cause cancer in humans,"[5] and in 1999, the EPA characterized the evidence carcinogenicity for lindane as "suggestive ... of carcinogenicity, but not sufficient to assess human carcinogenic potential. [41][44], The black box warning emphasizes that lindane should not be used on premature infants and individuals with known uncontrolled seizure disorders, and should be used with caution in infants, children, the elderly, and individuals with other skin conditions (e.g., dermatitis, psoriasis) and people who weigh less than 110 lb (50 kg), as they may be at risk of serious neurotoxicity. The authors concluded, "The California experience suggests elimination of pharmaceutical lindane produced environmental benefits, was associated with a reduction in reported unintentional exposures and did not adversely affect head lice and scabies treatment. [52] Today, the legally enforceable MCL standard for lindane is 200 ppt, while the national water criterion for lindane is 980 ppt.[52]. Pediculosis pubis (treatment)âLindane shampoo, [cream] , {29} and [ lotion] {27} {28} {29} are indicated for the treatment of pediculosis (lice) infestations caused by Pediculus humanus var. Even so, the CDC published in 2005 its Third National Report on Human Exposures to Environmental Chemicals, which found no detectable amounts of lindane in human blood taken from a random sampling of about 5,000 people in the US as part of the NHANES study (National Health and Nutrition Examination Survey at: https://www.cdc.gov/nchs/nhanes/about_nhanes.htm). Benzene hexachloride has six carbon atoms, six hydrogen atoms, and six chlorine atoms. [29] A recent analysis of the California ban concluded that a majority of pediatricians had not experienced problems treating lice or scabies since that ban took effect. benzene hexachloride isomers column gamma extraction Prior art date 1953-02-17 Legal status (The legal status is an assumption and is not a legal conclusion. Benzene hexachloride - General Information. [5] In the 1940s and 1950s, lindane producers stockpiled these isomers in open heaps, which led to ground and water contamination. 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