The resulting 95% credible region was 0.045 to 0.275, indicating little effect resulted from uncertainty in the denominator. The random-effect Bayesian metaanalysis yielded 95% credible intervals of 0.42%–1.69% and 0.08%–8.32%, respectively, for estimated SAR pooling from 15 case series and for predicted SAR in the future if pandemic continues. Since the denominator could actually have ranged from 31 to 38, the confidence interval was checked for robustness to errors in the denominator. of secondary cases = 2 no. Among 3795 susceptible individuals who had close contact with … We use cookies to help provide and enhance our service and tailor content and ads. DISCUSSION. Secondary attack rate = (17 ⁄ (86 − 18)) × 100% = (17 ⁄ 68) × 100% = 25.0% Incidence … ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Estimation of the secondary attack rate of COVID-19 using proportional meta-analysis of nationwide contact tracing data in Taiwan. Here, we propose a method for estimating the intrafamily SAR and SI from postings on the Twitter social network. The SAR is used to assess the transmissibility of disease and to evaluate control measures (1,2). The secondary attack rate is defined as the probability that infection occurs among susceptible persons within a reasonable incubation period following known contact with an infectious person or an infectious source. Published by Elsevier Taiwan LLC. Journal of Microbiology, Immunology and Infection, https://doi.org/10.1016/j.jmii.2020.06.003. Secondary attack rate (SAR) ... We calculated the crude SAR with the formula of “number of secondary confirmed cases/number of susceptible cases.” We then performed proportional meta-analyses by Bayes’ theorem to estimate the pooled SAR based on the current data and to predict SAR in the future if pandemic continues. Crude secondary attack rate (SAR) of COVID-19 in Taiwan was 0.84% using nationwide contact-tracing data till April 8, 2020. To date, such estimates have required extensive surveys of target populations. The secondary attack rate was estimated to be 13.2% (=5/[41-2-1]) (95% confidence interval 0.044 to 0.281). Copyright © 2020 Elsevier B.V. or its licensors or contributors. USES • To measure the spread of infection within a family, household or any closed aggregate of persons who have had contact with a case of disease. To identify the potential vehicle in a foodborne disease outbreak, the food-specific attack rate is often calculated, which is the attack rate for consumption of a specified food, calculated as number of cases of disease among people who ate food “X” number of persons who ate food “X” To calculate a measure of association between food “X” and illness, a second attack rate must be calculated for those who did … In infectious disease epidemiology, the household secondary attack rate (SAR) is the probability of disease transmission from an infected household member Ato a susceptible member Bduring A’s infectious period. If the 18 households included 86 persons, calculate the secondary attack rate. © 2020 Taiwan Society of Microbiology. Knowledge of the secondary attack rate (SAR) and serial interval (SI) of influenza is important for assessing the severity of seasonal epidemics of the virus. no. of children susceptible = 3 (excluding primary case) Therefore, SAR = 2/3 = 66.6% 5. It is a key epidemiologic parameter in infectious diseases that are transmitted by contact. By continuing you agree to the use of cookies. Calculate the secondary attack rate.