Since the applicant was not able to provide the full data from the studies described in the GRAS Notice No 375, the Panel could not consider the information for the current assessment. Les glycosides de stéviol, mieux connus sous le nom de ‘stévia’, sont extraits de la feuille de stévia (Stevia rebaudiana). The latest evaluation of steviol glycosides by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) took place in 2016 (JECFA, 2016). +39 0521 036 149E-mail: Press@efsa.europa.eu, Une science fiable pour des aliments sûrs, L'EFSA est une agence de l'Union européenne, Additifs alimentaires, Methodology, Allégations nutritionnelles et de santé, Pesticides, Ingrédients et emballages alimentaires, Matériaux en contact avec les aliments, Ingrédients et emballages alimentaires, Réévaluation des additifs alimentaires, Ingrédients et emballages alimentaires, Additifs alimentaires, Édulcorants. Stevia rebaudiana Les glycosides de stéviol ne sont pas assimilables par l’organisme. The Food and Drug Administration considers stevia extract (steviol glycosides) as GRAS-- generally recognized as safe 2. According to the FDA, steviol glycosides, which are obtained from the leaves of the stevia plant, are generally recognized as safe (GRAS).FDA approval as a food additive isn’t required. The active compounds within the plant, steviol glycosides, have been approved for human food and drink consumption by the FDA – the federal department of the USA which gives guidance on food safety and permits ingredients to be made commercially available. Considering that the complete hydrolysis of the glucosylated steviol glycosides was not demonstrated, toxicological data on steviol glycosides cannot be used in a read‐across approach to fully evaluate the safety of the glucosylated steviol glycoside preparations under evaluation. The applicant proposed that glucosylated steviol glycosides and parent steviol glycosides undergo a common metabolic process in pathway following ingestion and suggested that data from steviol glycosides can be used for read‐across to glucosylated steviol glycosides. Ou tout simplement besoin d’inspiration pour manger moins sucré ? The applicant stated that based on distribution analyses: the mono‐, di‐ and tri‐glucosylated are the predominant forms of the glucosylated steviol glycosides. Dossier ‘Application for authorisation of glucosylated steviol glycosides as a food additive in the European Union pursuant to Regulation (EC) No 1333/2008 of the European Parliament and the Council of 16 December 2008 on food additive’. The Panel noted that B. stearothermophilus and B. licheniformis are included in the list of qualified presumption of safety (QPS)‐recommended biological agents intentionally added to food or feed as notified to EFSA 5 (EFSA BIOHAZ Panel, 2017). This is achieved using enzymes that transfer glucose units from a starch source to the steviol glycosides, and results in the production of a mixture of glucosylated steviol glycosides (~80 to 92%) and non‐modified parent steviol glycosides (~5 to 15%). FDA approval as a food additive isn’t required. Le JEFCA a évalué les glycosides de stéviol et a contrôlé leur innocuité en 2008. The Panel further noted that the proposed glucosylated steviol glycosides preparations may contain up to 20 glucose moieties per molecule of steviol glycoside. Please check your email for instructions on resetting your password. The present scientific opinion deals with the evaluation of the safety of glucosylated steviol glycosides proposed for use as a new food additive in different food categories. OJ L 354, 31.12.2008, p. 16–33. https://doi.org/10.1016/j.fct.2012.10.016. The extract is then submitted to a series of purification and concentration steps and finally spray‐dried to yield a high‐purity stevia extract in powder form with a total steviol glycoside content of not less than 95%. EN VIDEO! The maximum limits proposed for toxic elements are much higher compared to the values obtained in the five batches analysed (< 0.005 mg/kg for As, Cd and Hg and < 0.054 mg/kg for Pb). Découvrez la recette de mojito à la fraise concoctée par notre blogueuse Everyday Marta. Note: This list is not exhaustive. Considering that the complete hydrolysis of the glucosylated steviol glycosides was not demonstrated, toxicological data on steviol glycosides cannot be used in a read‐across approach to fully evaluate the safety of the glucosylated steviol glycoside preparations under evaluation. According to the applicant, glucosylated steviol glycosides preparations consist of not less than 95% (on anhydrous basis) total steviol glycosides, made up of glucosylated steviol glycosides of different molecular weights as well as any remaining steviol glycosides. From analytical data provided within the application dossier, it can be observed that the proportion of each glucosylated steviol glycoside (mono‐, di‐, tri‐, poly‐glucosylated) in the commercial preparation depends on the composition of steviol glycosides in the starting material (> 95%) consisting of either rebaudioside A, rebaudioside D or a mixture of steviol glycosides. In the process, a mixture of glucosylated steviol glycosides containing from 1 to 20 additional glucose units bound to the parent steviol glycoside is generated. No further information on hydrolysis under realistic conditions was provided. Le groupe scientifique a établi une dose journalière acceptable (DJA)[1] de 4 mg par kg de poids corporel par jour pour les glycosides de stéviol, un niveau correspondant à celui déjà fixé précédemment par le comité mixte FAO/OMS d’experts en additifs alimentaires (JECFA).